Can I integrate Smartproxy residential proxies with a 3rd party software?

Of course, you can. Smartproxy proxies can be configured with all major automation bots. If your software runs on a dedicated server or on your local machine, simply add the machine IP to your whitelisted IP list. You can find more integration guides HERE.
You can configure Smartproxy proxies with all major automation bots.
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FYI:
1. Curious how does Smartproxy platform work? Check here
2. Want to know how can you use these proxies? Find here